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IMO a good thing is to start

IMO a good thing is to start with stating the purpose. Without that, and without an estimate of the allowed error, nothing can be done. For sensor characterization having light spectrum changing across the scene is a matter of concern. Exact experimental setup and flat field are the first order of business. Before that, any discussion of the need in demosaicking is premature.With decent setup demosaicking can be skipped, but the lightness error introduced by demosaicking is typically less than 2 dE.

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Iliah Borg